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Myoglobin (MYO) is applied for early screening of acute myocardial infarction and evaluation of striated muscle damage in patients with suspected muscle injury.
MYO OEM kit utilizes a two-antibody sandwich immunoassay and is applicable to chemiluminescence platforms. Specific antibodies target MYO epitopes to capture trace plasma MYO, delivering high sensitivity and specificity. Calibrated with high-purity recombinant MYO, the assay provides accurate and stable quantitative results. Serving as a vital early biomarker for acute myocardial infarction diagnosis, it supports early identification and dynamic monitoring of myocardial and skeletal muscle injury for clinical auxiliary diagnosis.
Myoglobin (MYO) is a protein uniquely present in human striated muscle and exists at low levels in healthy serum. It leaks into circulation when cardiac or skeletal muscle is injured. Thanks to its small molecular size, MYO elevates early: in AMI patients, levels increase 2–3 hours after symptom onset, peak within 7–10 hours and normalize around 24 hours, making MYO a key marker for AMI testing. Serum MYO assay aids diagnosis of myocardial infarction, muscular dystrophy, myocarditis and cardiomyopathy, as well as assessment of treatment response and prognosis.
★Bulk reagents are available with matching raw materials.
Marca :
QYM,SURFTECHArtículo n.° :
MYO-1Pedido (MOQ) :
On requestPago :
T/TOrigen del producto :
ChinaColor :
R1 should be a colorless to pale yellow transparent liquid; R2 should be a milky white suspension.Puerto de embarque :
Hefei or other portsPlazo de entrega :
On requestPeso :
On requestMYO OEM reagent
Product Specifications
| Product Name | MYO OEM reagent (chemiluminescence platforms) |
| Application: | It is applied for early screening of acute myocardial infarction and evaluation of striated muscle damage in patients with suspected muscle injury. |
|
Assay Principle: |
Two-antibody sandwich immunoassay |
|
Sample Type: |
Serum / Plasma |
|
Calibrator Component: |
Recombinant antigen |
|
Analytical Sensitivity |
10 ng/mL |
|
Functional Sensitivity |
21 ng/mL |
|
Measuring Range: |
10–3000 ng/mL |
|
Incubation Time |
5+3 min |
|
Calibration Interval |
28 days |
|
Precision: |
Intra-run CV ≤5%, Inter-run CV ≤8% |
|
Method Comparison: |
r＞0.975 vs. Roche |
|
Cross-reactivity |
≤0.0001% with hemoglobin at 1.06×10⁷ ng/L |
|
Interfering Substances |
Bilirubin <0.20 mg/mL; Total protein <100 g/L; Triglyceride <10 mg/dL |
|
Hook Effect Concentration |
30,000 ng/mL |
| Package Size |
on request |
| Storage/Shipping | Store sealed and protected from light at 2 °C to 8 °C |
| Shelf Life | 12 months |
Product Advantages
1.Linear correlation coefficient >0.99 within ≤3000 ng/mL, meets international criteria
2.High correlation vs Roche, R²＞0.975
3.Free of prominent hook effect under 30000 ng/mL
4.Acceptable recovery at 60× sample dilution
Linear Range Validation(pg/mL) Correlation to R* MYO Assay (human samples,n=40)
Application Scenarios
Myoglobin (MYO) is applied for early screening of acute myocardial infarction and evaluation of striated muscle damage in patients with suspected muscle injury.
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FAQ
What is the high-dose Hook effect limit for Myoglobin, given its extremely wide clinical dynamic range?
The assay incorporates an optimized antibody ratio to prevent false negatives, maintaining a high-dose Hook threshold exceeding 30,000 ng/mL.
How well does it correlate with global benchmark analyzers ?
High correlation vs Roche, R²＞0.975
What is the shelf life, lot-to-lot variation, and support for OEM bulk/uncut format supply?
Offers 12–18 months liquid stability (2–8℃) and lot-to-lot variation CV ≤8%. Available as liquid bulk, OEM test kits.
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